Pulmonary Hypertension and Aortic Stenosis

Pulmonary hypertension and sudden death in aortic stenosis.

Sudden death is now an infrequent occurrence in severe aortic stenosis. However, an impressive increase in pulmonary arteriolar resistance has been found in some patients with end-stage aortic stenosis dying suddenly or deteriorating suddenly after catheterisation. Pulmonary hypertension does not seem to cause sudden death, but, in conjunction with decreased cardiac output, a critical reduction...

Aortic Stenosis and Systemic Hypertension, Modeling Of

Aortic stenosis (AS) is the most common cardiovascular disease after hypertension and coronary artery disease and is the most frequent cause of valvular replacement in developed countries (1,2). This disease refers to the narrowing of the aortic valve opening during left ventricular (LV) ejection (Fig. 1a). This can be caused by a congenital abnormality of the valve (for example, the valve coul...

Aortic valve replacement improves survival in severe aortic stenosis associated with severe pulmonary hypertension.

BACKGROUND Severe pulmonary arterial hypertension in patients with severe aortic stenosis (AS) carries a poor prognosis. There are limited data on the effect of aortic valve replacement (AVR) in these patients. METHODS Our echocardiographic database between 1993 and 2003 was searched for patients with severe AS defined as a Doppler estimated aortic valve area of 0.8 cm2 or less and severe pul...

Pulmonary hypertension in mitral stenosis.

Determinants and prognostic significance of exercise pulmonary hypertension in asymptomatic severe aortic stenosis.

BACKGROUND Recent studies emphasized the usefulness of exercise stress echocardiography in asymptomatic patients with aortic stenosis. Nevertheless, the additive value of exercise pulmonary hypertension (Ex-PHT) in such patients remains unexplored. We therefore aimed to identify the determinants and to test the impact on outcome of Ex-PHT in asymptomatic patients with severe aortic stenosis. ...